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📄 Journal Article

Copper Acetate–DMSO Promoted Methylthiolation of Arenes and Heteroarenes

March 20, 2015 108 citations 🔒 Closed The Journal of Organic Chemistry
108
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Abstract

An unprecedented copper acetate-DMSO promoted methylthiolation of arenes and heteroarenes in the presence of air has been developed. The reaction is highly regioselective under the directing group influence of pyridine and pyrimidine functional units and gives the thiomethylated product in moderate to high yields.

Publication Details
TypeJournal Article
PublishedMarch 20, 2015
Source The Journal of Organic Chemistry
PublisherAmerican Chemical Society
Volume/Issue Vol. 80 , Issue 8 , pp. 4116-4122
DOI 10.1021/acs.joc.5b00443
OpenAlex ID W2329266697
Open AccessClosed Access